25年前Braunwald等就认为心脏是一种内泌器官,并认为由心肌及其神经产生,存贮并释放儿茶酚胺。多年来,心脏内分泌功能的概念毫无进展。近年来,一系列研究证实心房可以产生一种利钠与利水的因子。对于心脏病学家来说,接受人体某一局部能感受和调节循环负荷过重这一概念是合乎逻辑的。该部位必须是局限在循环系统特别是中心循环的低压区,即肺循环、心房以及肺静脉区。 Twenty-five years ago Braunwald et al. Considered the heart as an endocrine organ and believed that catecholamines were produced, stored, and released by the myocardium and its nerves. Over the years, there has been no progress in the concept of cardiac endocrine function. In recent years, a series of studies have confirmed that the atrium can produce a sodium and diuresis factor. It is logical for cardiologists to accept the notion that a part of the human body can feel and regulate a heavy cycle load. The site must be confined to the circulatory system, especially the central circulation of the low pressure area, the pulmonary circulation, atrium and pulmonary vein area.