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近年来,根据消化性溃疡的平衡学说的深入研究,抑制胃酸和胃蛋白酶等攻击因子,增强粘膜血流、粘液分泌等防御因子已成为今日治疗消化性溃疡的主要方法。本文就防御因子增强剂治疗消化性溃疡的进展综述如下。一、胃粘膜防御因子胃粘膜防御因子有粘液、重碳酸离子、细胞更新、粘膜血流(微循环)、磷脂质层的疏水屏障、消化道激素和最近注目的自身有效物质前列腺素(PG)。最近,上皮生长因子(EGF)和过氧化物歧化酶(SOD)亦受到重视。这些防御因子在发挥自身作用的同时,
In recent years, according to the theory of balance of peptic ulcer, in-depth study has shown that inhibition of attack factors such as gastric acid and pepsin, and enhancement of mucosal blood flow, mucus secretion and other defense factors have become the main methods for the treatment of peptic ulcer. This article on the defense factor enhancer treatment of peptic ulcer progress are summarized below. Gastric mucosal defensive factors Gastric mucosal defensive factors include mucus, bicarbonate ions, cellular renewal, mucosal blood flow (microcirculation), hydrophobic barriers to phospholipid layers, gastrointestinal hormones and the most recently noted prostaglandin (PG) . Recently, epithelial growth factor (EGF) and superoxide dismutase (SOD) have also been valued. These defensive factors play their role at the same time,