Graves 病是一个症候群,主要表现甲亢、弥漫性甲状腺肿大;小部分病人尚有眼病变、皮肤病变、杵状指以及指甲改变等。如患者表现特征性眼病而甲状腺机能仍然正常,则通常命名为正常甲状腺性 Graves 病。已有大量证据表明它是一种器官特异性自身免疫病,但没有一个单独的免疫学异常能解释所有的临床表现。作者就其病理生理、临 Graves disease is a syndrome, the main manifestations of hyperthyroidism, diffuse goiter; a small part of the patients there are eye disease, skin lesions, clubbing and nail changes. If the patient presents with a characteristic ocular disease and the thyroid function is still normal, it is usually named normal thyroid Graves disease. There is ample evidence that it is an organ-specific autoimmune disease, but none of the individual immunological abnormalities explain all clinical manifestations. The author on its pathophysiology, Pro