对578例新生儿发生医院感染进行分析,结果82例发生医院感染,感染率为14.2％,高于我院平均医院感染率(10.8％),感染部位主要为口腔、脐部、结膜、皮肤、呼吸道和消化道,主要病原菌为表皮葡萄球菌、不动杆菌、白色念珠菌。抗生素使用治疗用药为65.4％,预防用药34.6％。提示应严格掌握用药指征,减少和避免无指征及多联合用药,严格控制预防性应用抗生素。 Analysis of nosocomial infections in 578 newborns resulted in nosocomial infection in 82 patients, with an infection rate of 14.2%, which was higher than the average hospital infection rate (10.8%) in our hospital. The main infection sites were oral cavity, navel, conjunctiva, skin, Respiratory and gastrointestinal, the main pathogens Staphylococcus epidermidis, Acinetobacter, Candida albicans. Antibiotic use of medication was 65.4%, preventive medication 34.6%. Tips should be strictly controlled medication indications, to reduce and avoid no indications and more combined medication, strict control of prophylactic antibiotics.