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目的探讨急性期脑出血患者低钠血症的特点、发病机理及其对预后的影响。方法 对 118例急性脑出血患者的血清钠进行监测 ,将病后 2 4小时内、2 4～ 72小时、3～ 7天及 1周后的低钠血症发生率进行对比 ,并观察与出血量的关系及对预后的影响。结果 急性脑出血患者低钠血症在 3天内 ,3～ 7天及 1周后的发生率分别为 11.8%、16 .1%及 11.0 % ,无显著性差异 (P >0 .0 5 ) ,低钠血症发生率与出血量有一定关系 (P <0 .0 5 ) ,但并不影响患者预后 (P >0 .0 5 )。结论 急性期脑出血患者出现低钠血症与脑出血本身病理改变有关 ,其并发抗利尿激素分泌异常综合征 (SIADH)机率较低。
Objective To investigate the characteristics, pathogenesis and prognosis of hyponatremia in patients with acute cerebral hemorrhage. Methods Serum sodium in 118 patients with acute cerebral hemorrhage was monitored. The incidence of hyponatremia in 24 hours, 24 hours to 72 hours, 3 to 7 days and 1 week after the illness were compared and observed. The relationship between quantity and prognosis. Results The incidence of hyponatremia in patients with acute cerebral hemorrhage was 11.8%, 16.1% and 11.0% within 3 days, 3 to 7 days and 1 week respectively, with no significant difference (P> 0.05) The incidence of hyponatremia was related to the amount of bleeding (P <0.05), but it did not affect the prognosis of patients (P> 0.05). Conclusion The occurrence of hyponatremia in patients with acute cerebral hemorrhage is related to the pathological changes of cerebral hemorrhage. The incidence of SIADH is low.