系统性红斑狼疮(SLE)是一种自身免疫性疾病,主要表现在自身抗体与抗原结合成免疫复合物,在补体参与下,沉积于靶器官而致血管和器官的损害,常累及皮肤、关节、浆膜(包括胸膜、心包膜)、心、肾、肝、脾、血液、肺和神经等。肺胸病变的发生率也高。SLE肺胸膜病变的主要表现有:1.胸膜炎伴或不伴胸腔渗出液;2.各类型非感染性肺炎;3.肺部继发性感染,包括细菌、病毒、结核和真菌感染,以及弥漫性肺间质纤维化。一、发病率及死亡率1904年Oser首先报告伴有肺部浸润的SLE患者,虽然感染是引起肺浸润的常见原因,但在许多患者却与感染无关。近年来,国内报道SLE837例, Systemic lupus erythematosus (SLE) is an autoimmune disease that manifests itself in the combination of autoantibodies and antigens into immune complexes that, when involved in complement, deposit on target organs and cause damage to blood vessels and organs, often involving the skin and joints , Serosa (including pleura, pericardium), heart, kidney, liver, spleen, blood, lungs and nerves. The incidence of pulmonary thoracic lesions is also high. The main manifestations of SLE pulmonary pleuropulmonary lesions are: 1. pleuritis with or without pleural effusion; 2. various types of non-infectious pneumonia; 3. secondary pulmonary infections, including bacterial, viral, tuberculosis and fungal infections, and Diffuse pulmonary fibrosis. First, morbidity and mortality In 1904 Oser first reported SLE patients with pulmonary infiltrates, although infection is a common cause of pulmonary infiltrates, but in many patients has nothing to do with the infection. In recent years, domestic reports SLE837 cases,