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目的原发性中枢神经系统淋巴瘤（ＰＣＮＳＬ）较少见，但恶性高，现以９例作一临床分析。方法用病理和免疫组织化学检查证实９例ＰＣＮＳＬ，分析其诊断、治疗及预后。结果肿瘤位于大脑深部，呈浸润性生长，ＣＴ具有一定的特性，边界一般较清楚，呈略高密度，注射造影剂后增强明显。单纯的手术切除肿瘤无助于延长患者的生存期，多数病例预后恶劣。放疗和化疗有一定疗效。结论ＰＣＮＳＬ恶性高，发展快，早期诊断及治疗是延长患者生存期的关键。对脑内深部占位性病变应想到ＰＣＮＳＬ的可能。
Purpose The primary central nervous system lymphoma (PCNSL) is rare, but malignant, now a clinical analysis of 9 cases. Methods Nine cases of PCNSL were confirmed by pathology and immunohistochemistry. The diagnosis, treatment and prognosis were analyzed. Results The tumor was located deep in the brain and showed invasive growth. CT had certain characteristics. The border was generally clearer with a slightly higher density and markedly enhanced after injection of contrast agent. Simple surgical removal of the tumor does not help prolong the survival of patients, most cases of poor prognosis. Radiotherapy and chemotherapy have a certain effect. Conclusions PCNSL is highly malignant and develops rapidly. Early diagnosis and treatment are the key to prolong the survival of patients. Deep brain lesions in the brain should think PCNSL possible.