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目的:分析不同治疗方法在多囊卵巢综合征胰岛素抵抗患者中的临床治疗效果。方法:选取我院2015年1月-2017年1月诊治的100例多囊卵巢综合征胰岛素抵抗患者作为研究对象,然后随机、平均的将其分成每组50人的观察组与对照组,观察组患者行二甲双胍治疗,对照组行噻唑烷二酮类药物治疗,然后对两组患者治疗前后的胰岛素水平、卵泡刺激素等变化进行比较分析。结果:两组患者经治疗后,在体重指数、HI水平等在同组比较中,具有明显改善,且P<0.05,数据具有可比性。在组间比较中,观察组略优于对照组,且数据具有差异性,且P<0.01。结论:在患者胰岛素敏感性、高雄激素改善方面,二甲双胍与噻唑烷二酮类效果大致相同。但是,二甲双胍的治疗效果要明显优于噻唑烷二酮类药物,所以在多囊卵巢综合征治疗中,应优先使用效果突出的二甲双胍作为治疗药物。
Objective: To analyze the clinical effects of different treatment methods in patients with polycystic ovary syndrome and insulin resistance. Methods: 100 cases of polycystic ovarian syndrome patients with insulin resistance who were diagnosed and treated in our hospital from January 2015 to January 2017 were selected as the study subjects, and then randomly divided into observation group and control group The patients were treated with metformin, the control group was treated with thiazolidinediones, then the changes of insulin level and follicle stimulating hormone before and after treatment were compared between the two groups. Results: The two groups of patients after treatment, the body mass index, HI levels in the same group comparison, with significant improvement, and P <0.05, the data is comparable. In comparison between groups, the observation group was slightly better than the control group, and the data were different, and P <0.01. CONCLUSIONS: Metformin has approximately the same effect as thiazolidinediones in terms of insulin sensitivity and hyperandrogenism. However, the treatment of metformin should be significantly better than thiazolidinedione drugs, so in the treatment of polycystic ovary syndrome, should give priority to the use of effective metformin as a therapeutic drug.