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代谢组学是一种新兴的、用于定性和定量分析复杂生物样品中相对分子量小于1000 D的内源性分子代谢物的研究方法,可用于疾病标志物的发现、诊断、治疗及预后的判断。血虚证和血瘀证均为中医临床常见的证候类型,代谢组学能够从整体上反应血虚证和血瘀证机体代谢物谱的变化规律。本文就代谢组学在血虚证和血瘀证中的研究应用做一综述。
Metabolomics is an emerging research method for the qualitative and quantitative analysis of endogenous molecular metabolites with molecular weights less than 1000 D in complex biological samples and can be used for the detection, diagnosis, treatment and prognosis of disease markers . Blood deficiency syndrome and blood stasis syndrome are all common types of TCM syndromes. Metabolomics can reflect the changes of metabolites of blood-stasis syndrome and blood-stasis syndrome as a whole. This article reviews the research applications of metabonomics in blood deficiency syndrome and blood stasis syndrome.