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目的观察乳酸左旋氧氟沙星注射液和氧氟沙星注射液对下呼吸道感染的治疗效果。方法收集下呼吸道细菌性感染８６例，随机分为两组，治疗组以乳酸左旋氧氟沙星注射液治疗，对照组以氧氟沙星注射液治疗，剂量均每次２００ｍｇ静滴，每日两次，一疗程均１０天。结果两组临床有效率分别为９３．０８％和７９．０７％，两组无显著性差异（Ｘ２＝２．４３，Ｐ＞０．０５）。细菌阴转率与清除率分别为８９．２％、８１．６％与８６．８％、７７．５％，两组相似（Ｐ＞０．０５）。结论乳酸左旋氧氟沙星注射液抗菌活性强，临床应用疗效好，不良反应少，值得临床推广。
Objective To observe the therapeutic effect of levofloxacin lactate injection and ofloxacin injection on lower respiratory tract infection. Methods Eighty-six cases of bacterial infection of lower respiratory tract were collected and randomly divided into two groups. The treatment group was treated with levofloxacin lactate injection and the control group was treated with ofloxacin injection. The dosage was 200 mg intravenously every day Twice, a course of treatment is 10 days. Results The clinical efficacies of the two groups were 93.08% and 79.07% respectively, with no significant difference between the two groups (X2 = 2.43, P> 0.05). The rates of bacterial vaginosis and clearance were 89.2%, 81.6% and 86.8%, 77.5% respectively, which were similar between the two groups (P> 0.05). Conclusion Lactic acid levofloxacin injection has strong antibacterial activity, good curative effect in clinical application and few adverse reactions, which is worthy of clinical promotion.