用抗体、铁蛋白、酶和凝集素等通过交联技术标记生物活性分子,在医学研究中应用日广。此项技术的关键是保证交联后的结合物有满意的生物活性。传统的交联方法常用同型双功能试剂(homobifunctional reagent),所得结合物生物活性不理想。近年来多改用异型双功能试剂(heterobi- Labeling biologically active molecules with antibodies, ferritins, enzymes and lectins via cross-linking techniques is widely used in medical research. The key to this technology is to ensure that the cross-linked conjugate has satisfactory biological activity. The traditional cross-linking method commonly used homobifunctional reagent (homobifunctional reagent), the resulting conjugate biological activity is not ideal. In recent years, more use of heterobifunctional reagents (heterobi-