论文部分内容阅读
目的了解妇儿医院产ESBLs肺炎克雷伯菌的临床分布及耐药性。方法通过病原学标本检测和细菌鉴定技术,对宁波市妇儿医院住院患者医院感染标本进行调查与分析。结果该医院连续5年,从感染患者标本中共分离出肺炎克雷伯菌1 229株,2007-2011年鉴定出产ESBLs肺炎克雷伯菌构成比依次为54.7%、55.4%、46%、41.7%、47.0%。非产ESBLs肺炎克雷伯菌对亚胺培南敏感率为100%,产ESBLs肺炎克雷伯菌对亚胺培南耐药率<1.5%。结论妇儿医院住院患者感染肺炎克雷伯菌中,产ESBLs菌株构成比较高,对亚胺培南等抗菌药物尚比较敏感。
Objective To investigate the clinical distribution and drug resistance of Klebsiella pneumoniae producing ESBLs in women and children hospital. Methods The etiological specimens and bacterial identification techniques were used to investigate and analyze the nosocomial infection specimens of inpatients in Ningbo Women and Children Hospital. Results A total of 1 229 strains of Klebsiella pneumoniae were isolated from infected patients for 5 consecutive years. The constituent ratios of Klebsiella pneumoniae producing ESBLs from 2007 to 2011 were 54.7%, 55.4%, 46% and 41.7%, respectively, , 47.0%. The susceptibility of non-ESBLs-producing Klebsiella pneumoniae to imipenem was 100%, and the resistance rate of ESBLs-producing Klebsiella pneumoniae to imipenem was <1.5%. Conclusions In-patients with Klebsiella pneumoniae in women and children hospital have higher ESBLs-producing strains and are more sensitive to antibiotics such as imipenem.