巨细胞病毒(CMV)是器官移植后重要的感染原,其来源可以是内源或外源性的。受者免疫功能状态与 CMV 感染密切相关,它又通过直接感染免疫细胞和导致细胞因子调节紊乱进一步引起宿主免疫抑制。本文侧重对近几年其发病机理的研究作了归纳和分析。 Cytomegalovirus (CMV) is an important infectious agent after organ transplantation, and its origin may be endogenous or exogenous. Recipient immune status is closely related to CMV infection, which in turn leads to host immune suppression by directly infecting immune cells and causing disturbances in cytokine regulation. This article focuses on the study of its pathogenesis in recent years made a summary and analysis.