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尿素自血循环扩散至胃液时可在尿素酶作用下产生氨。尿素酶可来自细菌或/和粘膜。作者对7例正常人给予口服氨苄青霉素,每日4克,共7天。发现基础胃液氨从5.5±1.4降至1.8±0.3毫克分子,而乙胺吡唑(Betazole)刺激后的胃液氨则从4.7±0.9降至1.3±0.3毫克分子(P<0.01)。另各以7例正常人分别给予口服新霉素(每日4克)或肌注氨苄青霉素(每日4克),亦获得同样结果。对5名氮质血症病人采用同样的口服氨苄青霉素治疗,结果基础胃液氨
Urea from the blood circulation to the gastric juice can produce ammonia under the action of urease. Urease can come from bacteria and / or mucous membranes. The authors gave oral ampicillin orally to 7 normal people, 4 grams daily, for a total of 7 days. The basal gastric ammonia was found to decrease from 5.5 ± 1.4 to 1.8 ± 0.3 milligram, whereas gastric juice ammonia decreased from 4.7 ± 0.9 to 1.3 ± 0.3 milligram (P <0.01) after stimulation with Betazole. The other 7 normal people were given oral neomycin (4 g daily) or intramuscular ampicillin (4 g daily), also obtained the same result. On the five azotemia patients with the same oral ampicillin treatment, the results of the basic gastric ammonia