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目的探讨联合吸入复方异丙托溴铵和布地奈德治疗毛细支气管炎的疗效及安全性。方法将符合标准224例毛细支气管炎患儿随机分成A组为单纯吸入复方异丙托溴铵,B组为单纯吸入布地奈德,及C组为联合吸入复方异丙托溴铵和布地奈德分别进行治疗,观察比较三组疗效及安全性。结果 A组总有效率76.3%,B组总有效率77.3%,C组总有效率98.7%,A组与C组、B组与C组比较差异有统计学意义(P<0.05)。结论联合吸入复方异丙托溴铵和布地奈德治疗毛细支气管炎起效快,效果肯定,安全性好,可作为首选治疗。
Objective To investigate the efficacy and safety of combined inhalation of ipratropium bromide and budesonide in the treatment of bronchiolitis. Methods A total of 224 children with bronchiolitis were randomly divided into group A as simple inhalation of compound ipratropium bromide, group B as simple inhalation of budesonide, and group C as combined inhalation of compound ipratropium bromide and budesonide Respectively, for treatment, observe and compare the efficacy and safety of the three groups. Results The total effective rate of group A was 76.3%, the total effective rate of group B was 77.3%, the total effective rate of group C was 98.7%. There was significant difference between group A and group C, group B and group C (P <0.05). Conclusion Combined inhalation of compound ipratropium bromide and budesonide in the treatment of bronchiolitis has rapid onset, definite effect and good safety, which can be used as first choice treatment.