一、各种抗菌素之间的联合用药抗菌素联合应用时,一般情况是:两种以上的抑菌性抗菌素并用(如四环素加氯霉素)时,有累加作用;两种以上的杀菌性抗菌素并用时,则有协同作用;杀菌性抗菌素与抑菌性抗菌素并用时,有可能产生协同作用也可能产生拮抗作用,其临床表现不一。杀菌性抗菌素一般系指氨基甙类、先锋霉素类、多粘菌素类、青霉素类;抑菌性抗菌素则系指四环素类、氯霉素类、磺胺类、林可霉素类、红霉素类。杀菌性抗菌素与抑菌性抗菌素合用,表现为拮抗比较典型的例子是青霉素 G 加四环素类。因为细菌在繁殖期中, First, the combination of various antibiotics The combined use of antibiotics, the general situation is: more than two kinds of antibacterial antibacterial use (such as tetracycline plus chloramphenicol), the cumulative effect; two or more bactericidal antibiotics and When used, there is a synergistic effect; bactericidal antibiotics and bacteriostatic antibiotics, may have synergistic effect may also have antagonistic effects, its clinical manifestations vary. Bactericidal antibiotics generally refers to aminoglycosides, cephalosporins, polymyxins, penicillins; bacteriostatic antibiotics are tetracyclines, chloramphenicol, sulfonamides, lincomycin, erythromycin Class. Bactericidal antibiotics combined with antimicrobial antibiotics, the performance of antagonistic typical example is penicillin G plus tetracyclines. Because bacteria in the breeding season,