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目的:探索老年良性前列腺增生夜尿病因特点及相关因素。方法:选取49~84岁年龄段并已明确诊断为前列腺增生(BPH)的男性患者及没有进行过治疗或服用药物者120例。所有患者按照IPSS评分中夜尿频率从0~5分为6组,记录和测量研究对象的各项指标,包括国际前列腺症状评分(IPSS)、生活质量(QOL)、剩余尿量(PVR)、最大尿流率(Qmax)、前列腺体积(TPV)和排尿量(V)。结果:夜尿频率为0~1次者共38例(31.7%),平均QOL评分为2.43;夜尿频率为2~3次者共50例(41.7%),平均QOL评分为3.87;夜尿频率为4次以上者共32例(26.7%),平均QOL评分为5.23。不同组的夜尿频率BPH患者间的QOL评分具有显著性差异(P<0.05);多因素Logistic回归分析表明,BPH患者的年龄和PVR是夜尿频率增高的危险因素(P<0.05),而TPV和Qmax与夜尿频率的关系无统计学意义(P>0.05)。结论:夜尿频率的增多明显影响老年人的生活质量,并且随着老年人的年龄、残余尿量的增加,夜尿频率出现增加的趋势;但前列腺的体积和最大尿流率与夜尿频率无关。
Objective: To explore the causes and related factors of nocturnal causes of benign prostatic hyperplasia (BPH) in the elderly. Methods: A total of 120 male patients with 49- to 84-year-old BPH who had been diagnosed as having BPH and 120 patients without treatment or medication were enrolled. All patients were divided into 6 groups according to the IPSS score of nocturia from 0 to 5, and the indicators of the study were recorded and measured, including IPSS, QOL, PVR, Maximum flow rate (Qmax), prostate volume (TPV) and urine output (V). Results: There were 38 cases (31.7%) with nocturnal frequency of 0 ~ 1, mean QOL score was 2.43; nocturnal frequency was 2 ~ 3 times in 50 cases (41.7%), mean QOL score was 3.87; A total of 32 patients (26.7%) with a frequency of 4 or more had an average QOL score of 5.23. The QOL scores of nocturnal frequency BPH patients in different groups were significantly different (P <0.05). Multivariate logistic regression analysis showed that the age and PVR of BPH patients were the risk factors of nocturia (P <0.05) The relationship between TPV and Qmax and nocturia frequency was not statistically significant (P> 0.05). Conclusions: The increase of nocturia frequency obviously affects the quality of life of the elderly. With the increase of age and residual urine volume, the nocturia frequency tends to increase. However, the volume of the prostate and the maximal uroflow rate and nocturia frequency Nothing to do