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前瞻性研究41例20～27岁健康妇女服用低剂量口服避孕药(OCs)时骨代谢是否受维生素D受体基因多态性的影响。其中观察组21例,对照组20例,均为来门诊要求服药并自愿参加本研究的妇女。排除标准:有OCs的绝对或相对禁忌证;月经周期不规律;妊娠;12个月内曾分娩或哺乳;自然或人工流产6
Prospective study of 41 cases of 20 to 27-year-old healthy women taking low doses of oral contraceptives (OCs), bone metabolism is affected by the vitamin D receptor gene polymorphism. 21 cases in the observation group and 20 cases in the control group, all of whom came to the clinic for medication and voluntarily participated in the study. Exclusion criteria: absolute or relative contraindications to OCs; irregular menstrual cycle; pregnancy; childbirth or breastfeeding within 12 months; natural or induced abortion 6