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目的探讨卡前列素氨丁三醇注射液(欣母沛)治疗前置胎盘预防剖宫产产后出血的临床效果。方法 100例前置胎盘行剖宫产的产妇,随机分为观察组和对照组,各50例。两组患者均采取静脉滴注缩宫素治疗,在此基础上,对照组给予缩宫素联合米索前列醇治疗,观察组给予欣母沛治疗。比较两组患者在术中,术后2、24 h出血情况。结果观察组患者在术中,术后2、24 h后的平均出血量少于对照组,差异具有统计学意义(P<0.01)。两组不良反应发生率比较差异无统计学意义(P>0.05)。结论在临床前置胎盘产后出血的预防治疗上,采用欣母沛是一种非常有效的手段,值得临床推广。
Objective To investigate the clinical effect of carboprost trometamol injection (Xin-Pei-Pei) in preventing placenta previa bleeding after cesarean section. Methods 100 cases of placenta previa cesarean section of women, were randomly divided into observation group and control group, 50 cases each. Two groups of patients were treated with oxytocin intravenous infusion, on this basis, the control group was given oxytocin combined with misoprostol, the observation group was given Xinma Pei treatment. The two groups of patients were compared intraoperatively, postoperative bleeding at 2, 24 h. Results The mean amount of bleeding after surgery and postoperatively was less in the observation group than in the control group (P <0.01). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Preclinical placenta in the prevention and treatment of postpartum hemorrhage, the use of Yan Xin Pei is a very effective means, worthy of clinical promotion.