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从何首乌（PolygonummultiflorumThunb.）的根中分离出11个化合物，根据光谱学分析分别鉴定为：大黄酚（chrysophanol，Ⅰ）、大黄素甲醚（physcione，Ⅱ）、大黄素（emodin，Ⅲ）、ω-羟基大黄素（citreorosein，Ⅳ）、大黄酚8－O-β-D-吡喃葡萄糖苷（chrysophanol8-O-β-D-glucopyranoside，Ⅴ）、大黄素甲醚8-O-β-D-吡喃葡萄糖苷（Physcione8-O-β-D-glucopyranoside，Ⅵ）、大黄素8-O-β-D-吡喃葡萄糖苷（emodin8-O-β-D-glucopyranoside，Ⅶ）、决明酮8-O-β-D-吡喃葡萄糖苷（torachrysone8-O-β-D-glucopyranoside,Ⅷ）、2，3，5，4′-四羟基芪2-O-β-D-吡喃葡萄糖苷（2，3，5，4′－tetrahydroxystilbene2-O-β-D-glucopyranoside，Ⅸ）、没食子酸甲基酯（methylgallate，Ⅹ）和吲哚-3－（L-α-氨基-α-羟基内酸）甲酯[Indole－3－（L－α－amino－α－hydroxypropionicacid）methylester]。其中，化合物Ⅺ为新的天然产物。上述蒽醌和萘类化合物以及芦荟大黄素（aloe－emodin，Ⅻ）、大黄酸（rhein，）、芦荟大黄素8－O-β-D-吡喃葡萄糖苷（aloe－emodin8－O-β-D－glucopyranoside，）、大黄酚8－O-β-D－（6′－O-丙酰基）吡喃葡萄糖苷（chrysophanol8-O-β-D-（6′－O－malonyl）glucopyra－
Eleven compounds were isolated from the roots of Polygonum multiflorum Thunb. According to spectroscopic analysis, they were identified as chrysophanol (I), physcione (II), emodin (III), emodin (III), and ω - Citreorosein (IV), Chrysophanol 8-O-β-D-glucopyranoside (V), and Rhubarb methyl ether 8-O-β-D- Physcione8-O-β-D-glucopyranoside (VI), emodin8-O-β-D-glucopyranoside (VII), thamarone8 -O-β-D-glucopyranoside (torachrysone8-O-β-D-glucopyranoside (VIII), 2,3,5,4′-tetrahydroxypyrene2-O-β-D-glucopyranoside ( 2,3,5,4′-tetrahydroxystilbene2-O-β-D-glucopyranoside, IX), methylgallate (X) and indole-3-(L-α-amino-α-hydroxyactic acid ) Methyl ester [Indole-3-(L-α-amino-α-hydroxypropionic acid) methylester]. Among them, compound XI is a new natural product. The above-mentioned terpenes and naphthalene compounds and aloe-emodin (XII), rhein, aloe-emodin 8-o-β-D-glucopyranoside (aloe-emodin8-O-β- D-glucopyranoside,), Chrysophanol 8-O-β-D-(6′-O-propionyl)glucopyranoside (chrysophanol8-O-β-D-(6′-O-malonyl) glucopyra-