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1948年Patton A R 发现葡萄糖可以和蛋白发生某些化学反应。1969年Rahbar 证明糖化血红蛋白(HbA_1)的存在,并且发现在糖尿病人可增高2—3倍。血红蛋白以赖氨酸为主的氨基酸残基与葡萄糖发生非酶性结合,最终形成酮胺(胺—1—去氧果糖)。这种不可逆性反应仅受时间、浓度和温度影响。在红细胞生存期内不再改变。是对糖尿病在较长时间内控制情况的良好监测指标。本文通过对34例糖尿病人临床资料的分析,探讨糖化血红蛋白与血脂、血气及电解质等各项指标间的关系,并讨论“控制”的标
In 1948 Patton A R found that glucose can react with proteins in certain chemical reactions. In 1969 Rahbar proved the presence of HbA1 and found that it could be 2-3 times more often in diabetic patients. The lysine-based amino acid residues of hemoglobin are non-enzymatically bound to glucose, eventually forming ketamine (amine-1-deoxy fructose). This irreversible reaction is only affected by time, concentration and temperature. No change in the survival of red blood cells. Is a good indicator of diabetes control over a long period of time. In this paper, 34 cases of diabetes mellitus clinical data analysis to explore the relationship between glycated hemoglobin and blood lipids, blood gas and electrolytes and other indicators, and discuss the “control” of the standard