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目的探讨原发性高血压患者血脂综合指数与左心房增大的关系。方法从中山市黄圃人民医院选取资料完整且新诊断的原发性高血压患者150例,根据经胸超声心动图检查结果分为左心房增大组及左心房正常组。检测患者肾功能、血脂、血压、空腹血糖、血脂综合指数等指标并进行统计分析,采用Spearman进行相关分析,多因素Logistic回归分析左心房增大的相关因素。结果共有150例患者纳入本研究,左心房内径扩大者30例,左心房正常者120例,平均年龄(51.27±4.83)岁,两组间收缩压、血脂综合指数差异具有统计学意义(P<0.05),Spearman相关分析表明血脂综合指数与左心房大小呈正相关(r=0.563,P<0.05),多因素Logistic回归分析,结果显示血脂综合指数是左心房增大的危险因素(OR=1.985,95%CI:1.131~3.692,P<0.05)。结论在原发性高血压患者中,血脂综合指数与左心房增大呈正相关,并且是左心房增大的危险因素。
Objective To investigate the relationship between serum total lipids and left atrial enlargement in patients with essential hypertension. Methods 150 patients with complete and newly diagnosed essential hypertension were selected from Zhongshan Huangpu People’s Hospital. According to the results of transthoracic echocardiography, they were divided into the left atrium enlargement group and the left atrium normal group. The renal function, blood lipids, blood pressure, fasting blood glucose, blood lipid index and other indicators were measured and statistically analyzed, Spearman correlation analysis, multivariate Logistic regression analysis of the relevant factors of left atrial enlargement. Results A total of 150 patients were enrolled in this study. Thirty patients with enlarged left atrium and 120 normal left atria (mean age, 51.27 ± 4.83) years old had statistically significant differences in systolic blood pressure and blood lipid index (P < 0.05). Spearman correlation analysis showed that there was a positive correlation between total lipids and left atrium size (r = 0.563, P <0.05), and multivariate logistic regression analysis showed that the lipids comprehensive index was the risk factor of left atrium enlargement (OR = 1.985, 95% CI: 1.131 ~ 3.692, P <0.05). Conclusion In patients with essential hypertension, the lipids comprehensive index is positively correlated with the increase of left atrium, and is a risk factor for the increase of left atrium.