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目的:探讨整个孕期影响骨代谢的相关因素。方法:孕妇入院待产后取空腹血和晨尿测定尿钙(Ca)、肌酐(Cr)、血碱性磷酸酶(ALP),产后3天内测骨密度。根据孕期补钙及喝牛奶情况分为两组:孕20周以后补钙(元素钙500 mg/天以上)及喝牛奶(250 ml/天以上)持续16周以上的59例产妇为A组,未有效补钙及喝牛奶的58例产妇为B组。结果:初产年龄与左侧股骨颈骨密度值的高低有正相关性,A组左侧股骨颈骨密度高于B组,差异有统计学意义;B组产妇血ALP、尿Ca/Cr高于A组,差异有统计学意义。结论:孕期容易发生骨量减少,有效补钙可以防治孕期骨质疏松,降低骨转换率。
Objective: To investigate the related factors affecting bone metabolism during pregnancy. Methods: Pregnant women were admitted to hospital after delivery of fasting blood and morning urine urine calcium (Ca), creatinine (Cr), blood alkaline phosphatase (ALP), measured within 3 days postpartum bone mineral density. According to the situation of calcium supplement and milk during pregnancy, the patients were divided into two groups: 59 pregnant women with calcium supplement (calcium 500 mg / day or above) and milk (250 ml / day) for 16 weeks or more after 20 weeks of gestation were Group A, 58 cases of maternal women who did not drink calcium and drink milk effectively were Group B. Results: There was a positive correlation between the first trimester age and the left femoral neck BMD. The left femoral neck BMD in group A was higher than that in group B, the difference was statistically significant. The ALP, urinary Ca / Cr In group A, the difference was statistically significant. Conclusion: During pregnancy prone to reduce bone mass, effective calcium can prevent osteoporosis during pregnancy, reduce bone turnover.