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作者在94例淋巴网细胞瘤(何杰金氏病)患者中发现59％(56例)有皮肤表现。按传统分类法可把这些病变分为特异性和非特异性二种。特异性病变发生在真皮内,网状组织恶性增生,伴有不同程度的反应性肉芽肿。非特异性病变只表现为普通的炎症性变化。特异性皮肤表现发生率为3.5～7％,本组94例中有4例出现特异性病变,占4.2％。临床表现多样化:肿块、结节、浸润性斑块、溃疡、丘疹、斑疹,偶见恶性红皮病。这些病损的组织学变化符合淋巴网细胞瘤,尤其是肿块和结节性病损。表皮正常或轻度萎缩,
The authors found 59% (56 cases) of skin manifestations in 94 patients with lymphoblastoma (Hodgkin’s disease). According to the traditional classification of these lesions can be divided into two kinds of specificity and non-specific. Specific lesions occur in the dermis, reticular malignant hyperplasia, accompanied by varying degrees of reactive granulomas. Non-specific lesions showed only common inflammatory changes. Specific skin manifestations of 3.5 to 7%, 94 cases in this group, 4 cases of specific lesions, accounting for 4.2%. Diversification of clinical manifestations: lumps, nodules, infiltrative plaques, ulcers, papules, rash, occasionally malignant erythema. Histological changes in these lesions are in line with lymphoblastoma, especially in lumps and nodular lesions. Normal or mild epidermal atrophy,