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我院放疗科自1992年4月～1994年4月外照射加腔内距离放射治疗鼻咽癌70例,均经病理证实。首程治疗60例,鼻咽复发癌再程治疗10例。本组(结合组)与同期单纯外照射组的1、2、3年生存率没有明显统计学差异。两组中的鼻咽复发癌再程放疗的1、2、3年生存情况亦没有明显统计学差异。放疗后复发情况:结合组的鼻咽腔内复发率明显低于单纯外照射组,但其颅底与咽旁间隙的复发率,两组没有明显差异。采用腔内近距离放疗病人的鼻咽粘膜反应较单纯外照射重,鼻咽复发癌腔内放疗后易出现鼻咽出血。给我们的提示是:对鼻咽腔周围病变,外照射致局部控制没有把握时,不宜盲目行腔内近距离放疗。一般情况下,腔内近距离放疗只是腔内加量放疗,做为外照射的补充治疗,剂量不宜过高。
Radiotherapy department in our hospital from April 1992 to April 1994 external irradiation and radiotherapy in the treatment of nasopharyngeal carcinoma in 70 cases were confirmed by pathology. The first treatment of 60 cases of nasopharyngeal carcinoma recurrent treatment of 10 cases. This group (combination group) and the same period of simple external irradiation group 1, 2, 3-year survival rate no significant difference. No significant difference was found in the 1, 2, 3-year survival of nasopharyngeal carcinoma recurrence and radiotherapy in both groups. Recurrence after radiotherapy: The combined group of nasopharyngeal cavity recurrence rate was significantly lower than the simple external irradiation group, but the skull base and parapharyngeal space recurrence rate, there was no significant difference between the two groups. Nasopharyngeal mucosal reaction using intracavitary brachytherapy in patients with nasopharyngeal mucosal reaction than simple external irradiation, nasopharyngeal carcinoma recurrence after intracavitary radiotherapy prone nasopharyngeal bleeding. To our hint: the lesions around the nasopharynx, local control caused by external radiation is not sure, the line should not be blind brachytherapy. Under normal circumstances, intracavitary brachytherapy is only the amount of intraluminal radiation therapy, as a supplementary treatment of external radiation, the dose should not be too high.