新型佐剂 Cp G DNA的基本结构中含有未甲基化的双核苷酸 ,其最常见的形式是用抗核酸酶二硫代磷酸酯骨架制备的合成的寡脱氧核苷酸 ( Cp G ODN)。先前研究显示 ,含免疫刺激性基元的 Cp G ODN是肌肉 ( IM)注射或鼻内 ( IN)吸入蛋白的有效佐剂。在此作者评估了 Cp G ODN作为口服抗 The basic structure of the novel adjuvant CpG DNA contains unmethylated dinucleotides, the most common form of which is a synthetic oligodeoxynucleotide (CpG ODN) prepared with a nuclease-resistant dithiophosphate backbone . Previous studies have shown that CpG ODNs containing immunostimulatory mothers are effective adjuvants for intramuscular (IM) injections or intranasal (IN) inhaled proteins. Here the authors evaluated CpG ODN as oral anti-cancer