论文部分内容阅读
目的:评价伊班膦酸钠治疗肺癌骨转移性骨痛的效果。方法:将48例肺癌骨转移骨痛的患者,采用随机方法,分为治疗(A)组:给予重酒石酸长春瑞滨注射液+顺铂注射液(NVB 25 mg·m-2 d1,8+DDP 25 mg·m-2d1-3)即(NP方案)+伊班膦酸钠4 mg;对照(B)组:采用NP方案;观察3个周期,评价止痛效果。结果:A组止痛总有效率为83.3%,B组止痛总有效率为41.7%。A组疗效明显优于B组。结论:伊班膦酸钠可有效治疗肺癌骨转移引起的疼痛,且不良反应小。
Objective: To evaluate the effect of ibandronate sodium on bone metastasis of bone cancer in lung cancer patients. Methods: Forty-eight patients with bone-metastatic bone cancer of lung cancer were randomly divided into treatment group (A): Vinorelbine tartrate injection plus cisplatin injection (NVB 25 mg · m-2 d1, DDP 25 mg · m-2d1-3) (NP regimen) + ibandronate 4 mg; control group (B): NP regimen; 3 cycles were observed to evaluate the analgesic effect. Results: The total effective rate of analgesic in group A was 83.3%, while the total effective rate of analgesic in group B was 41.7%. The efficacy of group A was better than that of group B. Conclusion: Ibandronate sodium can effectively treat the pain caused by bone metastasis of lung cancer with less adverse reactions.