用2,3,4,6-四-O-乙酰-β-D-葡萄糖(3)和4′-酚羟基未加保护的4′-去甲表鬼(?)毒素(2)在三氟化硼-乙醚络合物催化下-20℃反应,直接缩合生成β-葡萄糖甙4,收率75％。糖甙化反应的立体化学过程取决于反应温度和四乙酰基葡萄糖的构型。同样的反应在0°和20℃进行时,β-和α-糖甙5的比例分别为84:16和27:73％。用四乙酰葡萄糖的a:β混和物(α:β=70:30)在-30℃进行糖甙化反应时,生成的糖甙产物 (2) was treated with 2,3,4,6-tetra-O-acetyl-β-D-glucose (3) and 4’-phenolic hydroxyl unprotected 4’- Borane - ether complex catalyzed reaction at -20 ℃, direct condensation of β-glucoside 4, the yield of 75%. The stereochemistry of a glycosylation reaction depends on the reaction temperature and the configuration of tetraacetylglucose. The same reaction was carried out at 0 ° and 20 ° C with ratios of β-and α-glycoside 5 of 84:16 and 27:73, respectively. When the glycosylation reaction was carried out at -30 ° C with the a: β mixture of tetraacetylglucose (α: β = 70: 30), the resulting glycoside product