众所周知,机械通气可引起和加重肺损伤,一个潜在的机制是生物创伤,这是一种由细胞因子起决定性因素的炎性反应。荷兰研究人员最近综述了有关细胞因子在通气导致的肺损伤(VILI)和多器官功能障碍综合征 (MODS)中作用的文献。共选中57 篇英文文献,包括离体、体外和临床实验,文章发表于Neth J Med杂忠。结果发现,机械通气(MV)可导致健康和受损伤的肺脏中细胞因子的下调。所涉及到的细胞因子包 It is well-known that mechanical ventilation can cause and aggravate lung injury. One potential mechanism is biological trauma, an inflammatory response that is a determinant of cytokines. Dutch researchers recently reviewed the literature on the role of cytokines in ventilator-induced lung injury (VILI) and multiple organ dysfunction syndrome (MODS). A total of 57 English articles were selected, including in vitro, in vitro and clinical trials. The article was published in Neth J Med. As a result, it has been found that mechanical ventilation (MV) leads to the down-regulation of cytokines in healthy and injured lungs. The cytokine package involved