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目的探讨早发型重度子痫前期患者的临床特点和对妊娠结局的影响。方法对吉安市中心医院2008～2010年收治的39例早发型重度子痫前期病例进行分析,根据其发病孕周分为3组,即A组(孕周<28周),B组(28周≤孕周<32周),C组(32周≤孕周<34周)。结果 3组患者并发症发生率比较,差异无统计学意义(P>0.05);3组间新生儿窒息率和围生儿死亡率比较,差异有统计学意义(P<0.05);B组期待治疗时间明显长于其他两组(P<0.05)。结论早发型重度子痫前期新生儿窒息率和围生儿死亡率随发病孕周延长而降低,应严格选择病例进行期待治疗,并严密监测母胎情况,适时选择合适的方式终止妊娠。
Objective To investigate the clinical features of early-onset severe preeclampsia and its effect on pregnancy outcome. Methods 39 cases of early-onset severe preeclampsia in Ji’an Central Hospital from 2008 to 2010 were divided into three groups according to their gestational age: group A (gestational age <28 weeks), group B (28 weeks ≤ gestational age <32 weeks), group C (32 weeks ≤ gestational age <34 weeks). Results There was no significant difference in complication rates between the three groups (P> 0.05). There was a significant difference in neonatal asphyxia and perinatal mortality between the three groups (P <0.05); group B was expected Treatment time was significantly longer than the other two groups (P <0.05). Conclusions The rate of neonatal asphyxia and perinatal mortality in early onset severe preeclampsia is decreased with the prolongation of the gestational age. The cases should be selected for treatment with strict expectation. The mother fetus should be closely monitored and the appropriate way to terminate the pregnancy should be timely.