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很多研究已证实，出生后早期在富于感官刺激的丰富环境（EC）中生存的动物，与在缺少这种刺激的贫乏环境（IC）或标准环境中生存的动物相比，空间认知能力明显提高，并伴有一系列脑形态学和生化改变。有关这一效应的机制了解不多。一氧化氮（NO），作为一种新发现的逆向信使，
Numerous studies have demonstrated that the spatial cognition of animals that survive early in the season in a sensory-stimulating rich environment (EC) compared to animals that survive in a poor environment (IC) or a standard environment lacking such stimuli Significantly increased, accompanied by a series of brain morphological and biochemical changes. Mechanisms about this effect are poorly understood. Nitric oxide (NO), as a newly discovered reverse messenger,