在病毒的刺激下,激活了的单核巨噬细胞分泌的白细胞介素-1、白细胞介素-6和肿瘤坏死因子具有显著的间接和直接抗病毒作用,同时也能促进人免疫缺陷病毒、单纯疱疹病毒和巨细胞病毒等病毒在宿主细胞内的增殖和表达.另一方面,人免疫缺陷病毒和乙型肝炎病毒等病毒也能影响单核细胞因子的合成与分泌.本文对这些复杂的相互作用进行了综述. Under the stimulation of the virus, activated mononuclear macrophages secrete interleukin-1, interleukin-6 and tumor necrosis factor have a significant indirect and direct antiviral effect, but also can promote human immunodeficiency virus, Herpes simplex virus and cytomegalovirus and other viruses in host cell proliferation and expression.On the other hand, human immunodeficiency virus and hepatitis B virus and other viruses can also affect the monocyte cytokine synthesis and secretion.In this paper, these complex The interaction is reviewed.