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本文目的是研究丙烯腈(AN)对内质网膜脂质的不饱和脂肪酸过氧化的影响,研究AN与细胞色素P450的结合以及它在肝微粒体内氧化的可能性。实验结果表明,AN的氧化增强作用只有在含有微粒体和细胞液的系统中才明显地
The purpose of this study was to investigate the effect of acrylonitrile (AN) on the unsaturated fatty acid peroxidation of lipids in the endoplasmic reticulum and the association of AN with cytochrome P450 and its potential for oxidization in liver microsomes. The experimental results show that the oxidative enhancement of AN is only evident in systems containing microsomes and cytosol