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INTRODUCTIONEradication of Helicobacter pylori,a bacteriumresiding in stomach and causing peptic ulcer disease,can be achieved by using combination therapiesconsisting of one or two antibiotics with a protonpump inhibitor (PPI).The major antibiotics widelyused in the regimens to eradicate H.pylori aremetronidazole and clarithromycin.However,resistance to these antibiotics by H.pylori affects
INTRODUCTION Eradication of Helicobacter pylori, a bacteriumresiding in stomach and causing peptic ulcer disease, can be achieved by using combination therapiesconsisting of one or two antibiotics with a protonpump inhibitor (PPI). The major antibiotics widely used in the regimens to eradicate H.pylori aremetronidazole and clarithromycin .However, resistance to these antibiotics by H.pylori affects