1病例资料患者女,50岁,因“胸闷气喘10年余,加重2个月”至门诊就诊。患者十余年来反复发作胸闷气喘,夜间多发,逐年加重。既往曾行激发试验提示阳性,曾使用信必可、沙丁胺醇、茶碱类药物,症状好转,停药后反复。近2个月来症状再次反复,门诊拟诊哮喘。患者从事厨师职业20余年,既往对油漆味、花粉、尘螨过敏,无过敏性鼻炎史,无吸烟饮酒史。患者门诊体检:神志清楚,双肺呼吸音粗,两肺均可及 A case data of female patients, 50 years old, because “chest tightness and asthma more than 10 years, increased 2 months ” to the clinic. Patients with recurrent chest tightness and asthma more than ten years, multiple at night, increasing year by year. In the past, the challenge test showed positive positivity, had used the letter will be available, salbutamol, theophylline drugs, symptoms improved, after stopping repeatedly. Nearly two months to repeat the symptoms, outpatient consultation diagnosis of asthma. Patients engaged in chef occupation for more than 20 years, the past on the paint smell, pollen, dust mite allergy, no history of allergic rhinitis, no history of smoking and drinking. Patient outpatient examination: Consciousness, lung breath sounds coarse, both lungs are accessible