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本文采用放射性免疫非平衡竞争法测定68例新生儿脐动脉血内皮素（endothelinET）的含量。其中正常新生儿组27例；胎儿异常组（脐带绕颈、宫内窘迫、二产程停滞、窒息儿）22例；孕母异常组（胎膜早破、妊高症、胎吸助产、子宫疤痕等）19例。结果显示：胎儿异常及孕母异常组与正常新生儿组比较，ET值明显增高（P＜0．001），正常新生儿组ET值高于正常成人。本研究提示：新生儿脐血内皮素的测定，有助于反映分娩的不同情况，并为进一步探讨ET的病理基础及临床意义提供理论基础。
In this paper, 68 cases of neonatal umbilical artery endothelin (endothelinET) content was determined by radioimmunoassay non-equilibrium competition method. Among them, there were 27 cases of normal newborn group, 22 cases of abnormal fetal group (umbilical cord around neck, intrauterine distress, stagnation of second stage of labor and suffocation), abnormal gestational age group (premature rupture of membranes, pregnancy-induced hypertension, Scars, etc.) 19 cases. The results showed that ET was significantly higher (P <0.001) in normal fetuses and normal fetuses than in normal neonates, and higher in normal neonates than in normal adults. This study suggests that the determination of neonatal cord blood endothelin can help reflect the different conditions of delivery and provide a theoretical basis for further exploration of the pathological basis and clinical significance of ET.