论文部分内容阅读
目的探讨地屈孕酮与黄体酮胶丸在先兆流产治疗中的应用价值。方法 67例先兆流产患者,随机分为观察组(34例)和对照组(33例)。观察组应用地屈孕酮治疗,对照组应用黄体酮胶丸治疗,对比两组患者的用药效果以及不良反应发生率。结果观察组保胎成功率是97.06%,不良反应发生率是5.88%;对照组保胎成功率是84.85%,不良反应发生率是15.15%,两组保胎成功率和不良反应发生率比较差异均有统计学意义(P<0.05);治疗后两组孕酮水平均高于治疗前(P<0.05),但治疗后组间孕酮水平对比差异无统计学意义(P>0.05)。结论与黄体酮胶丸相比,地屈孕酮在先兆流产治疗中的应用价值更突出,且药物安全性较高,保胎作用更强,适宜先兆流产患者使用。
Objective To investigate the value of dydrogesterone and progesterone capsules in the treatment of threatened abortion. Methods 67 cases of threatened abortion were randomly divided into observation group (34 cases) and control group (33 cases). The observation group was treated with dydrogesterone, while the control group was treated with progesterone capsules. The efficacy of the two groups and the incidence of adverse reactions were compared. Results The success rate of miscarriage in the observation group was 97.06% and the incidence of adverse reactions was 5.88%. The success rate of miscarriage in the control group was 84.85% and the incidence of adverse reactions was 15.15%. The success rate of miscarriage and the incidence of adverse reactions in the two groups were significantly different (P <0.05). After treatment, the levels of progesterone in both groups were higher than those before treatment (P <0.05), but there was no significant difference in progesterone level between the two groups after treatment (P> 0.05). Conclusion Compared with progesterone capsules, dydrogesterone is more effective in the treatment of threatened abortion, and its drug safety is higher, and the effect of miscarriage is stronger. It is suitable for patients with threatened abortion.