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三环抗抑郁剂治疗抑郁症的效果业已肯定。但在症状消失以后,使用延续治疗是否有益,则尚未弄清。本文目的在于研究使用三环抗抑郁剂(amitriptyline或imipramine)治疗已获痊愈的抑郁症病人,用同一药物延续治疗一段时期的效用。研究对象是92例经阿密替林(amitriptyline)或丙脒嗪(imipramine)(至少150毫克/日)治疗3～10
The efficacy of tricyclic antidepressants in the treatment of depression has been confirmed. However, the use of extended treatment after the symptoms have disappeared has not yet been clarified. The purpose of this paper is to study the use of amitriptyline or imipramine in the treatment of a patient who has been cured of depression and to extend the duration of treatment with the same agent. The study population consisted of 92 patients treated with amitriptyline or imipramine (at least 150 mg / day) for 3 to 10