本发明公开了一种乙酸顺和反-薄荷酮-8-硫醇酯的合成方法,以硫代薄荷酮为起始原料,包括以下步骤:乙酰化:在乙酸酐中加入硫代薄荷酮,催化剂选用无水乙酸钠,用量为0.1%~1%,蒸出反应过程中生成的乙酸,反应时间20~40小时; The invention discloses a method for synthesizing cis and trans-menthone-8-thiol acetate. The method comprises the following steps of using thione as starting material: acetylation: adding thione menthanone into acetic anhydride, The use of anhydrous sodium acetate, the amount of 0.1% to 1%, distilled off the acetic acid generated during the reaction, the reaction time is 20 to 40 hours;