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β-肾上腺素能阻滞剂现已广泛用作为降压药物。不管有无膜稳定性、内源性拟交感活性或心脏选择性,β-阻滞剂都有降低血压的作用。然而,无β-阻滞性能的心得安右旋异构体无降压作用。无论急性或慢性给药,β-阻滞剂均降低心排出量,开始时常有代偿性的周围阻力升高,所以血压维持不变,以后随着周围阻力下降,血压降低。在降压时,不影
Beta-adrenergic blockers are now widely used as antihypertensive drugs. With or without membrane stability, endogenous sympathomimetic activity, or cardiac selectivity, beta-blockers have a hypotensive effect. However, there is no antihypertensive effect of diazepam in the absence of beta-blocker properties. Both acute and chronic drug administration, β-blockers reduce cardiac output, initially compensatory peripheral resistance often increased, so the blood pressure remained unchanged, with the surrounding resistance decreased, blood pressure decreased. In the buck, no shadow