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为研究 IL- 6水平与新生儿宫内或产时感染所致败血症之间的关系。应用ELISA双夹心法检测了 72例脐血清 ,其中正常 5 2例 ,败血症 2 0例。结果显示 :正常脐血组 IL- 6 :中位数 0 .0 2 4ng/ml(范围≤ 0 .0 2 2 1～ 0 .0 5 31 ng/ml) ;败血症组 :中位数 :0 .1 730 ng/ml(范围 0 .0 2 6 6 0～ 1 .2 5 89ng/ml)。经秩和检验 ,P<0 .0 0 0 5 (单侧 )。结论 提示脐血 IL - 6水平与新生儿败血症的发生有一定关系 ,IL - 6可作为新生儿败血症的早期诊断指标。
To investigate the relationship between IL-6 levels and neonatal intrauterine or intrapartum infections caused by sepsis. 72 cases of umbilical cord serum were detected by ELISA sandwich method, of which 52 cases were normal and 20 cases were sepsis. The results showed that: the normal umbilical cord blood group IL-6: median 0. 024ng / ml (range ≤0.22 1 ~ 0. 0531 ng / ml); sepsis group: median: 1 730 ng / ml (range0.026 6 0-1.525 ng / ml). By rank sum test, P <0 0 0 5 (unilateral). Conclusions The level of IL - 6 in umbilical cord blood is related to the occurrence of neonatal sepsis. IL - 6 can be used as an early diagnostic indicator of neonatal sepsis.