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目的探讨总免疫球蛋白E(TIgE)检测在儿童呼吸道疾病诊断中的应用价值。方法采用微粒子全自动化学发光仪对在我院儿科住院的560例呼吸道疾病患儿和40例健康儿童进行TIgE检测。结果在560例呼吸道疾病患儿中有54例患儿TIgE结果显著升高。对54例TIgE结果异常患儿标本进行特异性免疫球蛋白E(SIgE)检测,其中48例患儿标本SIgE结果显著升高;6例SIgE结果无显著变化。但临床对54例患儿在原有治疗方案中加用脱敏治疗后都取得了显著的临床疗效。结论对儿童呼吸道疾病患儿进行 TIgE检测,有助于临床诊断患儿呼吸道疾病是否存在呼吸道变态反应,以便临床采取有效的治疗手段。“,”Objective To investigate detection of total immunoglobulin E (TIgE) in children's respiratory diseases in the diagnosis of value. Methods 560 cases of children with respiratory diseases and 40 cases of healthy children were tested TIgE by the micro particle automatic chemiluminescence. Results 54 children patients' total IgE results significantly increased in 560 case of children with respiratory diseases. 48 children patients' specific immunoglobulin E (SIgE) results significantly increased in 54 cases of TIgE results significantly increased. Others 6 cases of SIgE results no significantly changed. But to 54 children with TIgE results rising add desensitization therapy in original treatment clinical effect is remarkable. Conclusion TIgE were detected for children with respiratory diseases. Which is helpful to clinical diagnosis whether there are respiratory allergic reaction in children with respiratory diseases. So that the clinical take effective treatments.