局灶性节段性肾小球硬化（FSGS）是常见的肾小球损害，通常伴有蛋白尿或肾病综合征表现。老年人粥样硬化性肾血管病（RVD）正逐渐被认识，严重的单侧或双侧肾动脉狭窄常引起肾缺血和肾单位功能丧失，易患继发性FS-GS。RVD病人出现蛋白尿和肾病综合征已有报道，但对肾小球损害尚 Focal segmental glomerulosclerosis (FSGS) is a common glomerular lesion usually associated with proteinuria or nephrotic syndrome. Atherosclerotic renal vascular disease (RVD) is becoming increasingly recognized in the elderly. Severe unilateral or bilateral renal artery stenosis often causes renal ischemia and loss of nephron function, predisposing to secondary FS-GS. Proteinuria and nephrotic syndrome have been reported in patients with RVD, but with damage to glomeruli