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本品是美国Ciba制药公司Geigy药厂80年代初开发的第二代抗忧郁药,是一种广谱抗忧郁药。本药疗效与阿米替林,丙咪嗪相似,但起效更快,毒副作用小,本药还具安定作用,正常人口服50mg后易安静,有急倦感,脑电图显示α波呈轻度改变,睡眠明显改善,夜间觉醒减少。本药还具有抗组胺及抗胆碱作用,但无抗惊厥及降温作用。本品于1982年在世界首次上市,我国尚未生产。[化学名称](1)N-methyl-9,10-ethanoanthracene-9(10H)-propanamine hydrochloride(2)N-methyl-9,10-ethanoanthracene-9(10H)-propylamine hydrochloride
This product is the second generation anti-depressant developed by Geigy Pharmaceutical Factory of America Ciba Pharmaceutical Company in the early 1980s. It is a broad-spectrum antidepressant. The drug efficacy and amitriptyline, imipramine similar, but faster onset, side effects, the drug also has the role of stability, the normal population after oral administration of 50mg easy to have a sense of urgency, EEG shows α wave Showed a slight change, significantly improved sleep, decreased awakening at night. The drug also has antihistamine and anticholinergic effects, but no anticonvulsant and cooling effect. This product was first listed in the world in 1982, China has not yet produced. [Chemical Name] (1) N-methyl-9,10-ethanoanthracene-9 (10H) -propanamine hydrochloride (2) N-methyl-9,10- ethanoanthracene-9