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目的探讨中青年糖尿病前期人群发病趋势及特征。方法对2006-2009年济南市区200多个企事业单位60岁以下在职职工进行每年一次的健康查体流行病学调查。通过微机筛选出所有5.6 mmol/L≤空腹血糖(FPG)<7.0 mmol/L者(排除已确诊糖尿病药物控制血糖者),再经口服75 g葡萄糖耐量试验(OGTT)2 h PG分为空腹血糖受损(IFG)组及糖耐量受损(IGT)组,对其年检出率及人群分布特征做回顾性分析。结果糖调节受损(IGR)发生率呈逐年上升趋势,IGR占所有5.6 mmol/L≤FPG<7.0 mmol/L者的50%以上。IFG男性检出率大于女性,IGT男、女性检出率无统计学差异,与IGT相比IFG发病更趋于年轻化。IGT较IFG更具有代谢综合征的特征。结论济南市区中青年人群中糖尿病前期有逐年增加的趋势,应予以关注,综合评估,全面干预。
Objective To explore the prevalence and characteristics of middle-aged and young people with pre-diabetes. Methods An annual physical examination of epidemiological investigation of health workers in more than 200 enterprises and institutions under the age of 60 in Jinan City from 2006 to 2009 was conducted. All patients with 5.6 mmol / L≤7.0 mmol / L FPG (excluding those with confirmed diabetes mellitus) were screened by computer and then were divided into fasting plasma glucose (GGD) by oral glucose tolerance test (OGTT) (IFG) group and impaired glucose tolerance (IGT) group, the annual detection rate and population distribution were analyzed retrospectively. Results The incidence of impaired glucose regulation (IGR) showed an increasing trend year by year, with IGR accounting for more than 50% of all patients with a median of 5.6 mmol / L and less than FPG <7.0 mmol / L. The detection rate of IFG in males was higher than that in females. There was no significant difference in the detection rate of females and females among IGTs. The incidence of IFG tended to be younger than IGT. IGT is more metabolic syndrome than IFG. Conclusion There is a tendency that the prevalence of diabetes mellitus is increasing year by year in middle-aged and young people in Jinan City. Therefore, attention should be paid to comprehensive assessment and comprehensive intervention.