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目的:探讨绝经后子宫肌瘤的临床处理。方法:回顾性分析55例经手术的绝经后子宫肌瘤的临床病理情况。结果:55例患者平均年龄为56.54岁,平均绝经年数7.61年。以绝经后阴道出血就诊者占42%,以绝经后子宫肌瘤增大就诊者占20%,体检发现子宫增大诊断为子宫肌瘤者占22%,以腹痛就诊者占11%,以附件肿物就诊者占5%。病理结果:单发肌瘤占56.4%,多发肌瘤占43.6%。平滑肌瘤52例,特殊类型肌瘤3例。合并变性13例(23.6%),合并内膜增生者19例(34.5%),合并恶性者6例(10.9%),其中内膜癌3例(5.5%),子宫肉瘤2例(3.6%),腺肌瘤部分恶变1例(1.8%)。绝经年数>10年与≤10年组比较,合并恶性的比率分别为29.53%与2.63%,P<0.05,差异有显著性。结论:绝经后子宫肌瘤患者中,年龄>60岁,绝经年数>10年,并伴有阴道出血者,其合并恶性的比率明显升高,为恶性肿瘤的高危人群,临床应予以高度重视。
Objective: To investigate the clinical treatment of uterine fibroids after menopause. Methods: A retrospective analysis of 55 cases of postmenopausal uterine fibroids clinically and pathologically. Results: The average age of 55 patients was 56.54 years, the average number of menopause was 7.61 years. In postmenopausal vaginal bleeding treatment accounted for 42% of patients with postmenopausal uterine fibroids increased treatment of patients accounted for 20%, increased uterine examination found that the diagnosis of uterine fibroids accounted for 22% to 11% of patients with abdominal pain, with attachments Tumor patients accounted for 5%. Pathological results: single fibroids accounted for 56.4%, multiple fibroids accounted for 43.6%. 52 cases of leiomyoma, 3 cases of special type fibroids. There were 13 cases (23.6%) with degeneration, 19 cases (34.5%) with neointimal hyperplasia, 6 cases (10.9%) with malignant neoplasm, 3 cases (5.5%) with endometrial carcinoma, 2 cases of uterine sarcoma (3.6%), 1 case of malignant adenomyosis (1.8%). Menopausal years> 10 years and ≤ 10 years group, the proportion of malignant merger was 29.53% and 2.63%, P <0.05, the difference was significant. CONCLUSIONS: In the postmenopausal women with uterine fibroids, the age> 60 years, the number of menopause> 10 years, accompanied with vaginal bleeding, the malignant ratio was significantly elevated, which is a high risk population of malignant tumors, which should be highly valued in clinic.