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问:据说潘生丁用于心脏病人可造成心跳突停,已禁用于冠心病,不知是否属实?请对潘生丁用于冠心病作一评价。答:所传潘生丁用于心脏病人可造成心跳突停,已禁用于冠心病,纯属不确。潘生丁目前仍是临床上应用较为广泛的抗心绞痛药物。它的药理作用,主要通过抑制二磷酸腺甙的分解,使腺甙在细胞内积蓄,从而扩张冠状动脉。有人认为本药主要扩张壁面肌层的冠状动脉,或仅扩张较小的冠状动脉(或阻力动脉),或仅能扩张阻塞后的血管,使微血管前小动脉括约肌松弛,对改善冠状动脉供血不起作用。但这些看法尚待进一步证实。此外,潘生丁尚能抑制血小板粘聚度,因而具有一定抗凝作用,与阿司匹林合用,可预防冠心病、心肌梗塞的发生。对预防冠状动脉粥样硬化病
Q: It is said that Pan Sheng Ding for cardiac patients can cause sudden cardiac arrest, has been banned in coronary heart disease, I do not know whether it is true? Please for the evaluation of dipyridamole for coronary heart disease. A: The transmitted diphtheria Ding can be used for heart disease can cause sudden cardiac arrest, has been banned in coronary heart disease, is purely imprecise. Dipyridamole is still the most widely used anti-anginal drug in clinical practice. Its pharmacological effects, mainly through the inhibition of adenosine diphosphate decomposition, so that adenosine in the cell accumulation, thereby expanding the coronary arteries. Some people think that the main expansion of the drug of the wall of the coronary artery wall, or only the expansion of smaller coronary artery (or resistance artery), or only can expand the blocked blood vessels, the arteriolar sphincter relaxation, to improve coronary artery blood supply is not kick in. However, these views have yet to be further confirmed. In addition, dipyridamole can still inhibit platelet aggregation, which has a certain anticoagulant effect, combined with aspirin, can prevent coronary heart disease, myocardial infarction. To prevent coronary atherosclerosis