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目的回顾性分析复发性喉癌患者实施挽救性手术治疗保留喉功能的效果,为复发性喉癌的治疗提供参考。方法选取40例实施挽救性手术治疗且要求保留喉功能的复发性喉鳞状细胞癌的患者作为研究对象,观察治疗并发症和生存率。结果 6例(15.0%)患者发生并发症,主要并发症为颈部皮瓣下积血、感染,咽皮肤瘘和局部组织坏死、吻合口开裂,经积极对症治疗后均恢复,患者喉部发音和呼吸功能保留较好。术后肿瘤局部控制率较好(80%)。术后随访2年生存率82.5%(33/40)。结论保留喉部功能的手术治疗应对患者肿瘤发生部位、肿瘤类型、手术指征等综合考虑,同时,有效的抗癌治疗和规范的术后随访对于该类患者的预后具有十分重要的临床意义。
Objective To retrospectively analyze the effect of preserving laryngeal function in patients with recurrent laryngeal cancer through salvage surgery and provide reference for the treatment of recurrent laryngeal cancer. Methods Forty patients with recurrent laryngeal squamous cell carcinoma who underwent salvage surgery and required laryngeal function were enrolled in this study. The treatment complication and survival rate were observed. Results Complications were found in 6 patients (15.0%). The main complications were hemorrhage, infection, pharyngeal skin fistula and local tissue necrosis under the flap of the neck. The anastomosis was ruptured and recovered after aggressive symptomatic treatment. The laryngeal sounds And better retention of respiratory function. Postoperative local tumor control rate is better (80%). The follow-up 2-year survival rate was 82.5% (33/40). Conclusion Surgical treatment of preserving laryngeal function should be considered comprehensively in terms of tumor location, tumor type and operation indications. At the same time, effective anti-cancer therapy and standard follow-up are of great clinical significance for the prognosis of these patients.