格隆溴铵作为一种毒蕈碱受体拮抗剂是潜在的长效支气管扩张药物,有可能用于哮喘和慢性阻塞性肺病(COPD)的治疗。为了评价格隆溴胺与已知抗炎药联合应用是否具有协同抗炎作用,研究人员以人早期单核细胞作体外模型,分别检测了毒蕈碱受体(M受体)亚型mRNA在该细胞中的表达,分析了在 Glycopyrrolate, as a muscarinic receptor antagonist, is a potential long-acting bronchodilator and potentially used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). To evaluate whether glycopyrronectan has a synergistic anti-inflammatory effect in combination with known anti-inflammatory drugs, the researchers tested the expression of muscarinic receptor (M receptor) isoform mRNA in human monocytes in vitro as an in vitro model The expression in the cells was analyzed at