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目的观察酚妥拉明联合肝素治疗肺源性心脏病心力衰竭的疗效。方法将57例肺源性心脏病患者随机分为治疗组和对照组。对照组28例采用常规内科治疗方法;治疗组29例在对照组治疗基础上加用酚妥拉明与肝素,1次/d,7～10d为1个疗程,观察疗效。结果治疗组的显效率和总有效率分别为72.4%和89.6%,而对照组则分别为53.6%和75%,治疗组的疗效明显优于对照组,两者有显著性差异(P<0.05),且治疗组在血液流变学改善方面优于对照组。结论酚妥拉明与低分子肝素治疗肺源性心脏病心力衰竭的疗效佳,值得临床推广应用。
Objective To observe the efficacy of phentolamine combined with heparin in the treatment of heart failure with pulmonary heart disease. Methods 57 cases of patients with pulmonary heart disease were randomly divided into treatment group and control group. In the control group, 28 cases were treated by conventional medical therapy. In the treatment group, 29 cases were treated with phentolamine and heparin once a day for 7 days and 1 case for 7 days. The therapeutic effect was observed. Results The effective rate and total effective rate of the treatment group were 72.4% and 89.6%, respectively, while that of the control group was 53.6% and 75% respectively. The curative effect of the treatment group was significantly better than that of the control group (P <0.05 ), And the treatment group was better than the control group in the improvement of hemorheology. Conclusion The efficacy of phentolamine and low molecular weight heparin in the treatment of heart failure with pulmonary heart disease is good and worthy of clinical application.